Xiang-Guo Li | Research Team

Publications

Andriana P; Palani S; Liljenbäck H; Iqbal I; Oikonen V; Virta J; Makrypidi K; Rajander J; Atencio Herre E; Suni A; Jalkanen S; Knuuti J; Martinez-Pomares L; Pirmettis I; Li XG; Saraste A; Roivainen A, 2025. Macrophage mannose receptor CD206-targeted PET imaging in experimental acute myocardial infarction. EJNMMI Res 15(1):66

Xiang-Guo Li, 2024. Voices in Molecular Pharmaceutics: Meet Professor Xiang-Guo Li, an Expert in Radiopharmaceutical Chemistry and Positron Emission Tomography for Improved Imaging of Immunological Disorders and Brain Tumors. Mol Pharm 21(9):4189-4190

Dillemuth P; Lövdahl P; Karskela T; Ayo A; Ponkamo J; Liljenbäck H; Paunonen S; Kunnas J; Rajander J; Tynninen O; Rosenholm JM; Roivainen A; Laakkonen P; Airaksinen AJ; Li XG, 2024. Switching the Chemoselectivity in the Preparation of [(18)F]FNA-N-CooP, a Free Thiol-Containing Peptide for Targeted Positron Emission Tomography Imaging of Fatty Acid Binding Protein 3. Mol Pharm 21(8):4147-4156

Li A; Jaakkola MK; Saaresranta T; Klén R; Li XG, 2024. Analysis of sleep apnea research with a special focus on the use of positron emission tomography as a study tool. Sleep Med Rev 77:101967

Eichin D; Rahkila J; Li XG; Ekambaram R; Lassfolk R; Leino R; Savolainen J, 2024. Mannose receptor independent uptake of transmembrane glycocluster immunostimulant TADM by macrophages. Carbohydr Res 541:109166

Toyohara J; Vugts D; Kiss OC; Todde S; Li XG; Liu Z; Yang Z; Gillings N; Cazzola E; Szymanski W; Meulen NV; Reilly R; Taddei C; Schirrmacher R; Li Z; Lagebo YJ; Bentaleb N; Souza Albernaz M; Lapi S; Ramogida C; Mukherjee A; Ajenjo J; Deuther-Conrad W; Bourdeau C, 2024. Highlight selection of radiochemistry and radiopharmacy developments by editorial board. EJNMMI Radiopharm Chem 9(1):42

Andriana P; Fair-Mäkelä R; Liljenbäck H; Kärnä S; Iqbal I; Makrypidi K; Rajander J; Pirmettis I; Li XG; Jalkanen S; Saraste A; Salmi M; Roivainen A, 2024. Macrophage mannose receptor CD206 targeting of fluoride-18 labeled mannosylated dextran: A validation study in mice. Eur J Nucl Med Mol Imaging 51(8):2216-2228

Dillemuth P; Karskela T; Ayo A; Ponkamo J; Kunnas J; Rajander J; Tynninen O; Roivainen A; Laakkonen P; Airaksinen AJ; Li XG, 2024. Radiosynthesis, structural identification and in vitro tissue binding study of [(18)F]FNA-S-ACooP, a novel radiopeptide for targeted PET imaging of fatty acid binding protein 3. EJNMMI Radiopharm Chem 9(1):16

Bhowmik AA; Heikkilä TRH; Polari L; Virta J; Liljenbäck H; Moisio O; Li XG; Viitanen R; Jalkanen S; Koffert J; Toivola DM; Roivainen A, 2024. Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [(68)Ga]Ga-DOTA-Siglec-9 Positron Emission Tomography in Murine Models of Inflammatory Bowel Disease. Mol Imaging Biol 26(2):322-333

Nammas W; Paunonen C; Teuho J; Siekkinen R; Luoto P; Käkelä M; Hietanen A; Viljanen T; Dietz M; Prior JO; Li XG; Roivainen A; Knuuti J; Saraste A, 2024. Imaging of Myocardial α(v)β(3) Integrin Expression for Evaluation of Myocardial Injury After Acute Myocardial Infarction. J Nucl Med 65(1):132-138

Auchynnikava T; Äärelä A; Liljenbäck H; Järvinen J; Andriana P; Kovacs L; Rautio J; Rajander J; Virta P; Roivainen A; Li XG; Airaksinen AJ, 2023. Tetrazine Glycoconjugate for Pretargeted Positron Emission Tomography Imaging of trans-Cyclooctene-Functionalized Molecular Spherical Nucleic Acids. ACS Omega 8(48):45326-45336

Jahandideh A; Virta J; Li XG; Liljenbäck H; Moisio O; Ponkamo J; Rajala N; Alix M; Lehtonen J; Mäyränpää MI; Salminen TA; Knuuti J; Jalkanen S; Saraste A; Roivainen A, 2023. Vascular adhesion protein-1-targeted PET imaging in autoimmune myocarditis. J Nucl Cardiol 30(6):2760-2772

Miner MWG; Liljenbäck H; Virta J; Kärnä S; Viitanen R; Elo P; Gardberg M; Teuho J; Saipa P; Rajander J; Mansour HMA; Cleveland NA; Low PS; Li XG; Roivainen A, 2023. High folate receptor expression in gliomas can be detected in vivo using folate-based positron emission tomography with high tumor-to-brain uptake ratio divulging potential future targeting possibilities. Front Immunol 14:1145473

Andriana P; Makrypidi K; Liljenbäck H; Rajander J; Saraste A; Pirmettis I; Roivainen A; Li XG, 2023. Aluminum Fluoride-18 Labeled Mannosylated Dextran: Radiosynthesis and Initial Preclinical Positron Emission Tomography Studies. Mol Imaging Biol 25(6):1094-1103

Moisio O; Virta J; Yatkin E; Liljenbäck H; Palani S; Viitanen R; Miner MWG; Oikonen V; Tolvanen T; Vugts DJ; Taimen P; Li XG; Hollmén M; Jalkanen S; Roivainen A, 2023. Preclinical Evaluation of (89)Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis. J Nucl Med 64(4):555-560

Viitanen R; Virtanen H; Liljenbäck H; Moisio O; Li XG; Nicolini V; Richard M; Klein C; Nayak T; Jalkanen S; Roivainen A, 2022. [(68)Ga]Ga-DOTA-Siglec-9 Detects Pharmacodynamic Changes of FAP-Targeted IL2 Variant Immunotherapy in B16-FAP Melanoma Mice. Front Immunol 13:901693

Palani S; Miner MWG; Virta J; Liljenbäck H; Eskola O; Örd T; Ravindran A; Kaikkonen MU; Knuuti J; Li XG; Saraste A; Roivainen A, 2022. Corrigendum: Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-(18)F-Fluoroglutamine. Front Immunol 13:902544

Suilamo S; Li XG; Lankinen P; Oikonen V; Tolvanen T; Luoto P; Viitanen R; Saraste A; Seppänen M; Pirilä L; Hohenthal U; Roivainen A, 2022. (68)Ga-Citrate PET of Healthy Men: Whole-Body Biodistribution Kinetics and Radiation Dose Estimates. J Nucl Med 63(10):1598-1603

Palani S; Miner MWG; Virta J; Liljenbäck H; Eskola O; Örd T; Ravindran A; Kaikkonen MU; Knuuti J; Li XG; Saraste A; Roivainen A, 2022. Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-(18)F-Fluoroglutamine. Front Immunol 13:821423

Jahandideh A; Ståhle M; Virta J; Li XG; Liljenbäck H; Moisio O; Knuuti J; Roivainen A; Saraste A, 2021. Evaluation of [(68)Ga]Ga-NODAGA-RGD for PET Imaging of Rat Autoimmune Myocarditis. Front Med (Lausanne) 8:783596

Miner MWG; Liljenbäck H; Virta J; Helin S; Eskola O; Elo P; Teuho J; Seppälä K; Oikonen V; Yang G; Kindler-Röhrborn A; Minn H; Li XG; Roivainen A, 2021. Comparison of: (2S,4R)-4-[(18)F]Fluoroglutamine, [(11)C]Methionine, and 2-Deoxy-2-[(18)F]Fluoro-D-Glucose and Two Small-Animal PET/CT Systems Imaging Rat Gliomas. Front Oncol 11:730358

Grönman M; Moisio O; Li XG; Toimela T; Huttala O; Heinonen T; Knuuti J; Roivainen A; Saraste A, 2021. Association between [(68)Ga]NODAGA-RGDyK uptake and dynamics of angiogenesis in a human cell-based 3D model. Mol Biol Rep 48(6):5347-5353

Ståhle M; Hellberg S; Virta J; Liljenbäck H; Metsälä O; Li XG; Jauhiainen M; Saukko P; Ylä-Herttuala S; Nuutila P; Knuuti J; Saraste A; Roivainen A, 2021. Evaluation of glucagon-like peptide-1 receptor expression in nondiabetic and diabetic atherosclerotic mice using PET tracer (68)Ga-NODAGA-exendin-4. Am J Physiol Endocrinol Metab 320(5):E989-E998

Aime S; Al-Qahtani M; Behe M; Bormans G; Carlucci G; DaSilva JN; Decristoforo C; Duatti A; Elsinga PH; Kopka K; Li XG; Liu Z; Mach RH; Middel O; Passchier J; Patt M; Penuelas I; Rey A; Scott PJH; Todde S; Toyohara J; Vugts D; Yang Z, 2021. Highlight selection of radiochemistry and radiopharmacy developments by editorial board. EJNMMI Radiopharm Chem 6(1):13

Al-Qahtani M; Behe M; Bormans G; Carlucci G; Dasilva J; Decristoforo C; Elsinga PH; Kopka K; Li XG; Mach R; Middel O; Passchier J; Patt M; Penuelas I; Rey A; Scott PJH; Todde S; Toyohara J; Vugts D, 2021. Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January-June 2020). EJNMMI Radiopharm Chem 6(1):5

Elo P; Li XG; Liljenbäck H; Gardberg M; Moisio O; Miner M; Virta J; Saraste A; Srinivasarao M; Pugh M; Low PS; Knuuti J; Jalkanen S; Airas L; Lu YJ; Roivainen A, 2021. Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis. J Neuroinflammation 18(1):30

Viitanen R; Moisio O; Lankinen P; Li XG; Koivumäki M; Suilamo S; Tolvanen T; Taimen K; Mali M; Kohonen I; Koskivirta I; Oikonen V; Virtanen H; Santalahti K; Autio A; Saraste A; Pirilä L; Nuutila P; Knuuti J; Jalkanen S; Roivainen A, 2021. First-in-Humans Study of (68)Ga-DOTA-Siglec-9, a PET Ligand Targeting Vascular Adhesion Protein 1. J Nucl Med 62(4):577-583

Moisio O; Palani S; Virta J; Elo P; Liljenbäck H; Tolvanen T; Käkelä M; Miner MG; Herre EA; Marjamäki P; Örd T; Heinäniemi M; Kaikkonen MU; Zhang F; Srinivasarao M; Knuuti J; Low PS; Saraste A; Li XG; Roivainen A, 2020. Radiosynthesis and preclinical evaluation of [(68)Ga]Ga-NOTA-folate for PET imaging of folate receptor β-positive macrophages. Sci Rep 10(1):13593

Jahandideh A; Uotila S; Ståhle M; Virta J; Li XG; Kytö V; Marjamäki P; Liljenbäck H; Taimen P; Oikonen V; Lehtonen J; Mäyränpää MI; Chen Q; Low PS; Knuuti J; Roivainen A; Saraste A, 2020. Folate Receptor β-Targeted PET Imaging of Macrophages in Autoimmune Myocarditis. J Nucl Med 61(11):1643-1649

Roivainen A; Li XG; Ohrndorf S; van der Laken CJ, 2020. In Vivo Imaging of Inflammation and Infection 2019. Contrast Media Mol Imaging 2020:6824583

Sirén S; Dahlström KM; Puttreddy R; Rissanen K; Salminen TA; Scheinin M; Li XG; Liljeblad A, 2020. Candida antarctica Lipase A-Based Enantiorecognition of a Highly Strained 4-Dibenzocyclooctynol (DIBO) Used for PET Imaging. Molecules 25.

Miner MW; Liljenbäck H; Virta J; Merisaari J; Oikonen V; Westermarck J; Li XG; Roivainen A, 2020. (2S, 4R)-4-[(18)F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models. Mol Imaging Biol 22(4):969-978

Ståhle M; Kytö V; Kiugel M; Liljenbäck H; Metsälä O; Käkelä M; Li XG; Oikonen V; Saukko P; Nuutila P; Knuuti J; Roivainen A; Saraste A, 2020. Glucagon-like peptide-1 receptor expression after myocardial infarction: Imaging study using (68)Ga-NODAGA-exendin-4 positron emission tomography. J Nucl Cardiol 27(6):2386-2397

Elo P; Li XG; Liljenbäck H; Helin S; Teuho J; Koskensalo K; Saunavaara V; Marjamäki P; Oikonen V; Virta J; Chen Q; Low PS; Knuuti J; Jalkanen S; Airas L; Roivainen A, 2019. Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats. J Neuroinflammation 16(1):252

Hagert C; Siitonen R; Li XG; Liljenbäck H; Roivainen A; Holmdahl R, 2019. Rapid spread of mannan to the immune system, skin and joints within 6 hours after local exposure. Clin Exp Immunol 196(3):383-391

Chrusciel P; Yatkin E; Li XG; Jaakkola UM; Knuuti J; Jalkanen S; Roivainen A, 2019. Safety Study of Single-Dose Intravenously Administered DOTA-Siglec-9 Peptide in Sprague Dawley Rats. Int J Toxicol 38(1):4-11

Benkherouf AY; Taina KR; Meera P; Aalto AJ; Li XG; Soini SL; Wallner M; Uusi-Oukari M, 2019. Extrasynaptic δ-GABA(A) receptors are high-affinity muscimol receptors. J Neurochem 149(1):41-53

Kiugel M; Hellberg S; Käkelä M; Liljenbäck H; Saanijoki T; Li XG; Tuomela J; Knuuti J; Saraste A; Roivainen A, 2018. Evaluation of [(68)Ga]Ga-DOTA-TCTP-1 for the Detection of Metalloproteinase 2/9 Expression in Mouse Atherosclerotic Plaques. Molecules 23.

Silvola JMU; Li XG; Virta J; Marjamäki P; Liljenbäck H; Hytönen JP; Tarkia M; Saunavaara V; Hurme S; Palani S; Hakovirta H; Ylä-Herttuala S; Saukko P; Chen Q; Low PS; Knuuti J; Saraste A; Roivainen A, 2018. Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography. Sci Rep 8(1):9720

Roivainen A; Li XG; Nanni C; Cai W; Ohrndorf S, 2018. In Vivo Imaging of Inflammation and Infection. Contrast Media Mol Imaging 2018:3817871

Käkelä M; Luoto P; Viljanen T; Virtanen H; Liljenbäck H; Jalkanen S; Knuuti J; Roivainen A; Li XG, 2018. Adventures in radiosynthesis of clinical grade [(68)Ga]Ga-DOTA-Siglec-9. RSC Adv 8(15):8051-8056

Moisio O; Siitonen R; Liljenbäck H; Suomela E; Jalkanen S; Li XG; Roivainen A, 2018. Exploring Alternative Radiolabeling Strategies for Sialic Acid-Binding Immunoglobulin-Like Lectin 9 Peptide: [(68)Ga]Ga- and [(18)F]AlF-NOTA-Siglec-9. Molecules 23.

Kiugel M; Kytö V; Saanijoki T; Liljenbäck H; Metsälä O; Ståhle M; Tuomela J; Li XG; Saukko P; Knuuti J; Roivainen A; Saraste A, 2018. Evaluation of (68)Ga-labeled peptide tracer for detection of gelatinase expression after myocardial infarction in rat. J Nucl Cardiol 25(4):1114-1123

Virtanen H; Silvola JMU; Autio A; Li XG; Liljenbäck H; Hellberg S; Siitonen R; Ståhle M; Käkelä M; Airaksinen AJ; Helariutta K; Tolvanen T; Veres TZ; Saraste A; Knuuti J; Jalkanen S; Roivainen A, 2017. Comparison of (68)Ga-DOTA-Siglec-9 and (18)F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry. Contrast Media Mol Imaging 2017:7645070

Hellberg S; Silvola JMU; Kiugel M; Liljenbäck H; Savisto N; Li XG; Thiele A; Lehmann L; Heinrich T; Vollmer S; Hakovirta H; Laine VJO; Ylä-Herttuala S; Knuuti J; Roivainen A; Saraste A, 2017. 18-kDa translocator protein ligand (18)F-FEMPA: Biodistribution and uptake into atherosclerotic plaques in mice. J Nucl Cardiol 24(3):862-871

Li XG; Hagert C; Siitonen R; Virtanen H; Sareila O; Liljenbäck H; Tuisku J; Knuuti J; Bergman J; Holmdahl R; Roivainen A, 2016. (18)F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography. ACS Med Chem Lett 7(9):826-30

Keinänen O; Li XG; Chenna NK; Lumen D; Ott J; Molthoff CF; Sarparanta M; Helariutta K; Vuorinen T; Windhorst AD; Airaksinen AJ, 2016. A New Highly Reactive and Low Lipophilicity Fluorine-18 Labeled Tetrazine Derivative for Pretargeted PET Imaging. ACS Med Chem Lett 7(1):62-6

Rinne P; Hellberg S; Kiugel M; Virta J; Li XG; Käkelä M; Helariutta K; Luoto P; Liljenbäck H; Hakovirta H; Gardberg M; Airaksinen AJ; Knuuti J; Saraste A; Roivainen A, 2016. Comparison of Somatostatin Receptor 2-Targeting PET Tracers in the Detection of Mouse Atherosclerotic Plaques. Mol Imaging Biol 18(1):99-108

Publication list retrieved from NCBI using ImpactPubs

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Other Publications

Torrieri G; Iqbal I; Fontana F; Talman V; Liljenbäck H; Andriana P; Nammas W; Rajander J; Li X-G; Low P; Teesalu T; Roivainen A; Hirvonen J; Ruskoaho H; Balasubramanian V; Saraste A; Santos H A; 2023.  Macrophage Hitchhiking Nanoparticles for the Treatment of Myocardial Infarction. Advanced Functional Materials, 33:2303658

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